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EP 3 930 888 A1

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(43) Date of publication: 05.01.2022 Bulletin 2022/01 (21) Application number: 20824402.0 (22) Date of filing: 25.11.2020

(51) International Patent Classification (IPC):  B01J 19/00(2006.01) B01L 3/00(2006.01) C12Q 1/6806(2018.01) (52) Cooperative Patent Classification (CPC): B01L 2200/0668; B01J 2219/00509; B01J 2219/00596; B01J 2219/00623; B01J 2219/00621; B01L 3/502761; B01J 2219/00608; B01J 2219/00286; B01L 2400/086; B01J 2219/00743; B01J 2219/00664; B01J 2219/00432; C12Q 1/6874; B01J 2219/00511; B01J 2219/00644; B01J 2219/00659; B01J 19/0046; B01J 2219/00722; C12Q 1/6806; B01J 2219/00585   C-Sets: C12Q 1/6874, C12Q 2523/308, C12Q 2527/125, C12Q 2535/122; C12Q 1/6806, C12Q 2523/308, C12Q 2527/125, C12Q 2535/122; (86) International application number: PCT/US2020/062163 (87) International publication number: WO 2021/108499 (03.06.2021 Gazette 2021/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.11.2019 US 201962941197 P 27.11.2019 US 201962941215 P 27.11.2019 US 201962941242 P 20.12.2019 NL 2024527 20.12.2019 NL 2024528 31.12.2019 NL 2024596 (71) Applicant: Illumina Inc San Diego CA 92122 (US)

(72) Inventors: KHURANA, Tarun, Kumar San Diego, CA 92122 (US) ROSAS-CANYELLES, Elisabet San Diego, CA 92122 (US) WU, Yir-shyuan San Diego, CA 92122 (US) BLACK, Hayden San Diego, CA 92122 (US) LESSARD-VIGER, Mathieu San Diego, CA 92122 (US) ZIMMERLEY, Max San Diego, CA 92122 (US) RAMIREZ, Sean San Diego, CA 92122 (US) (74) Representative: Arnold & Siedsma  Bezuidenhoutseweg 57 2594 AC The Hague 2594 AC The Hague (NL)