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EP 3 935 077 A1

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(43) Date of publication: 12.01.2022 Bulletin 2022/02 (21) Application number: 20715646.4 (22) Date of filing: 06.03.2020

(51) International Patent Classification (IPC):  C07K 14/705(2006.01) C07K 14/72(2006.01) C07K 14/47(2006.01) C12N 9/06(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/4702; C07K 14/70578; C07K 14/721; C07K 2319/00; C07K 2319/33; C12N 9/003 (86) International application number: PCT/US2020/021582 (87) International publication number: WO 2020/185628 (17.09.2020 Gazette 2020/38)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 08.03.2019 US 201962815404 P 18.04.2019 US 201962835554 P 12.06.2019 US 201962860356 P (71) Applicant: Obsidian Therapeutics, Inc. Cambridge, MA 02138 (US)

(72) Inventors: SCHEBESTA, Michael Cambridge, MA 02138 (US) FLEURY, Michelle, Lois Cambridge, MA 02138 (US) ELPEK, Kutlu, Goksu Cambridge, MA 02138 (US) WEISMAN, Elizabeth, Jane Jamaica Plain, MA 02130 (US) SURI, Vipin Belmont, MA 02478 (US) SUN, Dexue Cambridge, MA 02138 (US) LI, Dan, Jun Cambridge, MA 02138 (US) SHAMAH, Steven, Mark Acton, MA 01720 (US) BRISKIN, Michael, Joseph Lexington, MA 02421 (US) RICHARDSON, Celeste Brookline, MA 02467 (US) KASSUM, Tariq, A. Boston, MA 02108 (US) OLS, Michelle, Lynn Northborough, MA 01532 (US) DOLINSKI, Brian Cambridge, MA 02138 (US) INNISS, Mara, Christine Beverly, MA 01915 (US) BRIDEAU, Emily Cambridge, MA 02140 (US) GORI, Jennifer, Leah Jamaica Plain, MA 02130 (US) SETHI, Dhruv, Kam Westwood, MA 02090 (US) (74) Representative: Murgitroyd & Company  Murgitroyd House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)