(19)

(11)

EP 3 941 586 A1

(12)

(43) Date of publication: 26.01.2022 Bulletin 2022/04 (21) Application number: 20773768.5 (22) Date of filing: 20.03.2020

(51) International Patent Classification (IPC):  A61P 31/04(2006.01) C07D 277/64(2006.01) C07C 279/12(2006.01) (52) Cooperative Patent Classification (CPC): C07D 213/82; C07C 2601/08; C07D 213/68; C07D 239/34; C07C 279/24; C07B 2200/07; C07D 261/12; C07C 279/28; C07C 279/12; A61P 31/04 (86) International application number: PCT/US2020/023994 (87) International publication number: WO 2020/191348 (24.09.2020 Gazette 2020/39)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.03.2019 US 201962821926 P (71) Applicant: Cortexyme, Inc. South San Francisco, CA 94080 (US)	(72) Inventors: GALEMMO JR., Robert A. San Francisco, California 94080 (US) KONRADI, Andrei W. San Francisco, California 94080 (US) LYNCH, Casey C. San Francisco, California 94080 (US) DOMINY, Stephen S. San Francisco, California 94080 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)