(19)
(11) EP 3 946 322 A1

(12)

(43) Date of publication:
09.02.2022 Bulletin 2022/06

(21) Application number: 20717971.4

(22) Date of filing: 27.03.2020
(51) International Patent Classification (IPC): 
A61K 31/41(2006.01)
A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/41
(86) International application number:
PCT/IB2020/052959
(87) International publication number:
WO 2020/201967 (08.10.2020 Gazette 2020/41)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 29.03.2019 US 201962826078 P
17.05.2019 US 201962849535 P

(60) Divisional application:
21208101.2
21208102.0

(71) Applicant: Novocure GmbH
6039 Root (CH)

(72) Inventors:
  • TRAN, David
    Gainesville, Florida 32606 (US)
  • LE, Son Bang
    Gainesville, Florida 32610 (US)
  • CHEN, Dongjiang
    Gainesville, Florida 32608 (US)

(74) Representative: Carpmaels & Ransford LLP 
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB)

   


(54) METHODS FOR RESTORING SENSITIVITY TO TTFIELDS IN TTFIELDS-RESISTANT CANCER CELLS WITH PTGER3 INHIBITORS