A CLASS OF SMALL-MOLECULE COMPOUNDS AND THEIR PRODRUGS FOR INTERVENTION WITH CAMK2A, AND THEIR USE IN ACUTE BRAIN INJURIES AND CENTRAL HYPERSOMNIAS - Patent 3952873

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EP 3 952 873 A1

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(43)	Date of publication:
	16.02.2022 Bulletin 2022/07

(21)	Application number: 20702191.6

(22)	Date of filing: 21.01.2020

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International Patent Classification (IPC):

A61K 31/5025^(2006.01)

C07D 487/04^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	C07D 487/04

(86)	International application number:
	PCT/DK2020/050022

(87)	International publication number:
	WO 2020/151795 (30.07.2020 Gazette 2020/31)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	KH MA MD TN

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Priority:

21.01.2019 DK PA201970040

(71)	Applicant: Københavns Universitet
	1165 København K (DK)

(72)	Inventors:
	FRØLUND, Bente 2920 Charlottenlund (DK) WELLENDORPH, Petrine 2800 Kgs. Lyngby (DK) KORNUM, Birgitte Rahbek 1855 Frederiksberg C (DK)

(74)	Representative: Chas. Hude A/S
	Langebrogade 1,2., B2 1411 Copenhagen K 1411 Copenhagen K (DK)

(54)	A CLASS OF SMALL-MOLECULE COMPOUNDS AND THEIR PRODRUGS FOR INTERVENTION WITH CAMK2A, AND THEIR USE IN ACUTE BRAIN INJURIES AND CENTRAL HYPERSOMNIAS