(19)

(11)

EP 3 953 465 A1

(12)

(43) Date of publication: 16.02.2022 Bulletin 2022/07 (21) Application number: 20716828.7 (22) Date of filing: 09.04.2020

(51) International Patent Classification (IPC):  C12N 15/10(2006.01) (52) Cooperative Patent Classification (CPC): C12Y 205/01054; C12N 15/70; C12N 9/1085; C12N 2310/20 (86) International application number: PCT/EP2020/060260 (87) International publication number: WO 2020/208191 (15.10.2020 Gazette 2020/42)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 10.04.2019 LU 101172 10.04.2019 DE 102019109423 (71) Applicant: Technische Universität Hamburg 21073 Hamburg (DE)	(72) Inventors: ZENG, An-Ping 21224 Rosengarten (DE) CHEN, Lin 21073 Hamburg (DE) CHEN, Minliang 21073 Hamburg (DE) (74) Representative: Stüven, Ralf et al RGTH Patentanwälte PartGmbB Kirchenhang 32b 21073 Hamburg 21073 Hamburg (DE)