(19)

(11)

EP 3 958 862 A1

(12)

(43) Date of publication: 02.03.2022 Bulletin 2022/09 (21) Application number: 20795747.3 (22) Date of filing: 08.04.2020

(51) International Patent Classification (IPC):  A61K 31/433(2006.01) A61K 31/404(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/433; A61K 31/343; A61K 31/4045; A61K 31/428; A61K 31/4168; A61K 45/06   C-Sets: A61K 31/4168, A61K 2300/00; A61K 31/343, A61K 2300/00; A61K 31/433, A61K 2300/00; A61K 31/4045, A61K 2300/00; A61K 31/428, A61K 2300/00; (86) International application number: PCT/US2020/027238 (87) International publication number: WO 2020/219270 (29.10.2020 Gazette 2020/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 22.04.2019 US 201916390276 (71) Applicant: Knobler, Robert L. Fort Washington, PA 19034 (US)	(72) Inventor: Knobler, Robert L. Fort Washington, PA 19034 (US) (74) Representative: Gevers Patents  Intellectual Property House Holidaystraat 5 1831 Diegem 1831 Diegem (BE)