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(11)

EP 3 962 488 A1

(12)

(43) Date of publication: 09.03.2022 Bulletin 2022/10 (21) Application number: 19927207.1 (22) Date of filing: 30.04.2019

(51) International Patent Classification (IPC):  A61K 31/55(2006.01) A61K 9/00(2006.01) A61K 45/06(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/55; A61P 25/28 (86) International application number: PCT/US2019/029885 (87) International publication number: WO 2020/222799 (05.11.2020 Gazette 2020/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: La Pharma Tech Inc. Blacksburg, VA 24060 (US)	(72) Inventors: WANG, Jianmin Blacksburg, VA 24060 (US) CUI, Geping Blacksburg, VA 24060 (US) (74) Representative: Witthoff Jaekel Steinecke Patentanwälte PartG mbB  Postfach 1140 52412 Jülich 52412 Jülich (DE)