| (84) |
Designated Contracting States: |
|
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL
NO PL PT RO RS SE SI SK SM TR |
| (30) |
Priority: |
31.05.2019 US 201916428865
31.12.2019 US 201962956059 P
|
| (43) |
Date of publication of application: |
|
09.03.2022 Bulletin 2022/10 |
| (73) |
Proprietor: Universal Diagnostics, S.A. |
|
41013 Sevilla (ES) |
|
| (72) |
Inventors: |
|
- BITENC, Marko
1000 Ljubljana (SI)
- KRUUSMAA, Kristi
1000 Ljubljana (SI)
- MARTINEZ-BAREA, Juan
41013 Sevilla (ES)
- HENSE, Christian
41013 Sevilla (ES)
- SOLA DE LOS SANTOS, Pol
41013 Sevilla (ES)
- CANAL NOGUER, Pol
41013 Sevilla (ES)
- CHERSICOLA, Marko
1000 Ljubljana (SI)
- KNAP, Primoz
1000 Ljubljana (SI)
|
| (74) |
Representative: Carlos Hernando, Borja |
|
Garrigues IP, S.L.P.
Hermosilla, 3
28001 Madrid
28001 Madrid (ES) |
| (56) |
References cited: :
EP-A2- 2 977 467
WO-A2-2012/167145
|
WO-A1-2015/153283
|
|
| |
|
|
- HAIDAN YAN ET AL: "Identifying CpG sites with different differential methylation frequencies
in colorectal cancer tissues based on individualized differential methylation analysis",
ONCOTARGET, vol. 8, no. 29, 18 July 2017 (2017-07-18), pages 47356-47364, XP055723769,
DOI: 10.18632/oncotarget.17647
- FELIX KORDOWSKI ET AL: "Aberrant DNA methylation of ADAMTS16 in colorectal and other
epithelial cancers", BMC CANCER, vol. 18, no. 1, 6 August 2018 (2018-08-06) , XP055723762,
DOI: 10.1186/s12885-018-4701-2
- MICHAIL GALANOPOULOS ET AL: "Abnormal DNA methylation as a cell-free circulating DNA
biomarker for colorectal cancer detection: A review of literature", WORLD JOURNAL
OF GASTROINTESTINAL ONCOLOGY, vol. 9, no. 4, 1 January 2017 (2017-01-01) , page 142,
XP055723984, ISSN: 1948-5204, DOI: 10.4251/wjgo.v9.i4.142
- K Kruusmaa ET AL: "MSRE-qPCR for analysis of gene specific methylation can be accurately
used for detection and validation of colorectal cancer-specific patterns", 4Bio Summit,
Rotterdam 2018, 1 January 2018 (2018-01-01), XP055723835, Retrieved from the Internet:
URL:https://www.universaldx.com/wp-content /uploads/2017/05/4Bio-poster-November-2018
.pdf [retrieved on 2020-08-19]
- A. A. MELNIKOV: "MSRE-PCR for analysis of gene-specific DNA methylation", NUCLEIC
ACIDS RESEARCH, vol. 33, no. 10, 2 June 2005 (2005-06-02), pages e93-e93, XP055278893,
ISSN: 0305-1048, DOI: 10.1093/nar/gni092
|
|
