(19)
(11) EP 3 968 962 A1

(12)

(43) Date of publication:
23.03.2022 Bulletin 2022/12

(21) Application number: 19816509.4

(22) Date of filing: 16.10.2019
(51) International Patent Classification (IPC): 
A61K 9/14(2006.01)
A61K 31/4745(2006.01)
 A61K 9/19(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/4745; A61K 9/19; A61K 9/14; A61K 31/12
 
C-Sets:
  1. A61K 31/4745, A61K 2300/00;
  2. A61K 31/12, A61K 2300/00;
(86) International application number:
PCT/CZ2019/050048
(87) International publication number:
WO 2020/088702 (07.05.2020 Gazette 2020/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 30.10.2018 CZ 20180591
09.10.2019 CZ 20190630

(71) Applicant: Tomas Bata University In Zlín
76001 Zlín (CZ)

(72) Inventors:
  • XIAO, Haijun
    Chengdu, Sichuan (CN)
  • SEDLARIK, Vladimir
    76302 Zlin, Malenovice (CZ)

(74) Representative: Kreizlova, Dana 
Tomas Bata University in Zlin Nam. T.G. Masaryka 5555
760 01 Zlin
760 01 Zlin (CZ)

   


(54) METHODS OF MAKING NANOCRYSTALS WITH ENHANCED BIOLOGICAL AVAILABILITY AND FORMULATION FOR SUCH NANOCRYSTALS PREPARATION FOR USE IN ANTICANCER THERAPY