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(11)

EP 3 972 954 A1

(12)

(43) Date of publication: 30.03.2022 Bulletin 2022/13 (21) Application number: 20726476.3 (22) Date of filing: 21.05.2020

(51) International Patent Classification (IPC):  C07D 205/04(2006.01) A61P 21/00(2006.01) A61K 31/397(2006.01) (52) Cooperative Patent Classification (CPC): C07D 205/04; C07C 57/145; C07C 57/15; C07B 2200/13 (86) International application number: PCT/EP2020/064211 (87) International publication number: WO 2020/234423 (26.11.2020 Gazette 2020/48)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.05.2019 EP 19175593 (71) Applicant: Synthon B.V. 6545 CM Nijmegen (NL)	(72) Inventors: DYMACEK, Bohumil 67817 Blansko (CZ) PARTL, Jiri 678 01 Blansko (CZ) (74) Representative: Dobsík, Martin  Synthon B.V. Microweg 22 P.O. Box 7071 6503 GN Nijmegen 6503 GN Nijmegen (NL)