(19)

(11)

EP 3 976 017 A1

(12)

(43) Date of publication: 06.04.2022 Bulletin 2022/14 (21) Application number: 20813466.8 (22) Date of filing: 01.06.2020

(51) International Patent Classification (IPC):  A61K 31/167(2006.01) A61K 45/06(2006.01) A61K 31/423(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/423; A61K 31/661; A61K 31/662 (86) International application number: PCT/US2020/035592 (87) International publication number: WO 2020/243720 (03.12.2020 Gazette 2020/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 31.05.2019 US 201962855560 P (71) Applicant: Plex Pharmaceuticals, Inc. San Diego, California 92121 (US)	(72) Inventors: PRASAD, Sridhar Govinda San Diego, California 92129 (US) PETERMAN, Marshall Clarke Oceanside, California 92054 (US) SINHA, Santosh Ladera Ranch, California 92694 (US) (74) Representative: Patentanwälte Bressel und Partner mbB  Potsdamer Platz 10 10785 Berlin 10785 Berlin (DE)