(19)
(11) EP 3 980 126 A1

(12)

(43) Date of publication:
13.04.2022 Bulletin 2022/15

(21) Application number: 20732523.4

(22) Date of filing: 05.06.2020
(51) International Patent Classification (IPC): 
A61P 35/00(2006.01)
A61K 31/4745(2006.01)
A61K 31/5377(2006.01)
 C07D 471/04(2006.01)
A61K 31/496(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 471/04; A61P 35/00
(86) International application number:
PCT/EP2020/065730
(87) International publication number:
WO 2020/245430 (10.12.2020 Gazette 2020/50)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 07.06.2019 GB 201908171

(71) Applicant: Instituto de Medicina Molecular João Lobo Antunes
1649-028 Lisboa (PT)

(72) Inventors:
  • SEIXAS, João
    1649-028 Lisbon (PT)
  • BERNARDES, Gonçalo
    1649-028 Lisbon (PT)

(74) Representative: Pereira da Cruz, Joao 
J. Pereira da Cruz, S.A. Rua Victor Cordon, 10-A
1249-103 Lisboa
1249-103 Lisboa (PT)

   


(54) BENZO[H][1,6] NAPHTHYRIDIN-2(1H)-ONES AS BMX INHIBITORS, FOR USE AGAINST CANCER