(19)
(11) EP 3 986 410 A1

(12)

(43) Date of publication:
27.04.2022 Bulletin 2022/17

(21) Application number: 20825571.1

(22) Date of filing: 18.06.2020
(51) International Patent Classification (IPC): 
A61K 31/519(2006.01)
 A61K 39/395(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/519; A61K 45/06; A61K 31/7068; A61K 31/555; A61K 31/7048; G01N 2800/52; G01N 33/574; G01N 2333/70539; C12Q 1/485; C07K 16/2827; A61K 2039/505
 
C-Sets:
  1. A61K 31/519, A61K 2300/00;
  2. A61K 31/7068, A61K 2300/00;
  3. A61K 31/555, A61K 2300/00;
  4. A61K 31/7048, A61K 2300/00;
(86) International application number:
PCT/US2020/038557
(87) International publication number:
WO 2020/257536 (24.12.2020 Gazette 2020/52)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 18.06.2019 US 201962863153 P
27.09.2019 US 201962907375 P

(71) Applicant: G1 Therapeutics, Inc.
Research Triangle Park, NC 27709 (US)

(72) Inventors:
  • ROBERTS, Patricks, Joseph
    Research Triangle Park, NC 27709 (US)
  • LAI, Anne
    Research Triangle Park, NC 27709 (US)
  • SORRENTINO, Jessica
    Research Triangle Park, NC 27709 (US)

(74) Representative: Carpmaels & Ransford LLP 
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB)

   


(54) PATIENT SELECTION FOR ENHANCEMENT OF ANTI-TUMOR IMMUNITY IN CANCER PATIENTS