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(11)

EP 3 986 431 A1

(12)

(43) Date of publication: 27.04.2022 Bulletin 2022/17 (21) Application number: 20751824.2 (22) Date of filing: 18.06.2020

(51) International Patent Classification (IPC):  A61K 35/74(2015.01) A61K 9/20(2006.01) A61P 37/08(2006.01) A61K 45/06(2006.01) (52) Cooperative Patent Classification (CPC): A61K 35/74; A61P 37/08; A61K 45/06; A61K 9/0019; A61K 9/2004; A61K 9/2072; A61K 9/4816 (86) International application number: PCT/US2020/038335 (87) International publication number: WO 2020/257390 (24.12.2020 Gazette 2020/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.06.2019 US 201962864886 P 04.10.2019 US 201962910920 P (71) Applicant: Evelo Biosciences, Inc. Cambridge, MA 02139 (US)	(72) Inventors: CORMACK, Taylor, A. Cambridge, MA 02139 (US) ITANO, Andrea Cambridge, MA 02139 (US) PONICHTERA, Holly Cambridge, MA 02139 (US) RAMANI, Kritika Cambridge, MA 02139 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)