(19)

(11)

EP 3 990 456 A1

(12)

(43) Date of publication: 04.05.2022 Bulletin 2022/18 (21) Application number: 20830551.6 (22) Date of filing: 26.06.2020

(51) International Patent Classification (IPC):  C07D 471/04(2006.01) C07D 519/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; A61P 31/00; C07D 401/14 (86) International application number: PCT/US2020/039816 (87) International publication number: WO 2020/264292 (30.12.2020 Gazette 2020/53)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 26.06.2019 US 201962867003 P (71) Applicant: X4 Pharmaceuticals, Inc. Cambridge, Massachusetts 02139 (US)	(72) Inventors: BOURQUE, Elyse Marie Josee L'Etang-du-Nord Québec G4T3G6 (CA) SKERLJ, Renato West Newton, Massachusetts 02465 (US) (74) Representative: Tostmann, Holger Carl  Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Partnerschaft mbB Zweibrückenstrasse 5-7 80331 München 80331 München (DE)