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EP 3 990 626 A1

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(43) Date of publication: 04.05.2022 Bulletin 2022/18 (21) Application number: 20831651.3 (22) Date of filing: 26.06.2020

(51) International Patent Classification (IPC):  C12N 5/0783(2010.01) C07K 16/28(2006.01) A61P 35/00(2006.01) C07K 16/30(2006.01) A61K 35/17(2015.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 2317/622; C07K 16/303; C07K 14/7051; C07K 2319/03; C07K 2319/33; A61K 2039/5156; C07K 16/2803; C07K 2317/73; A61K 39/001174; A61K 39/001112; C12N 2740/16043; C07K 14/70517; C07K 14/70578; C07K 14/70596; C07K 2319/00; C07K 2319/02; C07K 2319/43 (86) International application number: PCT/IB2020/056097 (87) International publication number: WO 2020/261231 (30.12.2020 Gazette 2020/53)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.06.2019 US 201962867503 P 12.08.2019 WO PCT/KR2019/010244 16.12.2019 US 201916715462 18.03.2020 US 202062991493 P 03.04.2020 US 202063004827 P 24.06.2020 US 202063043237 P (71) Applicant: Eutilex Co., Ltd. Seoul 08591 (KR)

(72) Inventors: KWON, Byoung S. Seoul 08591 (KR) KIM, Kwanghee Seoul 08591 (KR) CHUNG, Jiwon Seoul 08591 (KR) CHANG, Young Gyoon Seoul 08591 (KR) YI, Bo-Rim Seoul 08591 (KR) LEE, Jungyun Seoul 08591 (KR) LEE, Sae Rom Seoul 08591 (KR) SON, Hyuntae Seoul 08591 (KR) LEE, Hye Mi Seoul 08591 (KR) YOO, Eun Hye Seoul 08591 (KR) (74) Representative: D Young & Co LLP  120 Holborn London EC1N 2DY London EC1N 2DY (GB)