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(11)

EP 3 990 630 A1

(12)

(43) Date of publication: 04.05.2022 Bulletin 2022/18 (21) Application number: 20831413.8 (22) Date of filing: 25.06.2020

(51) International Patent Classification (IPC):  C12N 9/22(2006.01) C12Q 1/68(2018.01) C12Q 1/6825(2018.01) C12N 15/10(2006.01) C12Q 1/6811(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6825; C12N 9/22   C-Sets: C12Q 1/6825; (86) International application number: PCT/US2020/039678 (87) International publication number: WO 2020/264204 (30.12.2020 Gazette 2020/53)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.06.2019 US 201962866312 P 01.07.2019 US 201916459298 09.06.2020 US 202063036772 P (71) Applicant: AMMR Joint Venture La Jolla, CA 92039 (US)	(72) Inventors: ARAN, Kiana Pasadena, California 91105 (US) KANE, Alexander Santa Cruz, California 95060 (US) GOLDSMITH, Brett San Diego, California 92128 (US) PAYTAVI, Regis Costa Mesa, California 92626 (US) (74) Representative: Woodhill, Matthew James et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)