(19)

(11)

EP 3 999 636 A1

(12)

(43) Date of publication: 25.05.2022 Bulletin 2022/21 (21) Application number: 20841623.0 (22) Date of filing: 17.07.2020

(51) International Patent Classification (IPC):  C12N 9/10(2006.01) C12N 11/02(2006.01) C12N 9/90(2006.01) C12P 19/02(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/90; C12P 19/02; C12N 11/02; C12N 9/1051; C12N 9/92; C12N 9/1205; C12Y 204/01001; C12Y 504/02002; C12Y 204/01024; C12Y 503/01009; C12Y 207/01144; C12Y 501/03015; C12P 19/18; C12P 19/24 (86) International application number: PCT/US2020/042562 (87) International publication number: WO 2021/011881 (21.01.2021 Gazette 2021/03)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 17.07.2019 US 201962875321 P 22.10.2019 US 201962924323 P (71) Applicant: Bonumose Inc. Charlottesville VA 22911 (US)	(72) Inventors: WICHELECKI, Daniel, Joseph Charlottesville, VA 22911 (US) WAGNER, Jonathan Waynesboro, VA 22980 (US) (74) Representative: Jacobi, Markus Alexander  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstrasse 4 68163 Mannheim 68163 Mannheim (DE)