(19)

(11)

EP 4 003 313 A1

(12)

(43) Date of publication: 01.06.2022 Bulletin 2022/22 (21) Application number: 20744080.1 (22) Date of filing: 29.07.2020

(51) International Patent Classification (IPC):  A61K 31/00(2006.01) C07D 311/16(2006.01) C07D 311/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 311/18; A61K 31/37; A61K 45/06; G01N 2333/98; G01N 2500/04 (86) International application number: PCT/EP2020/071401 (87) International publication number: WO 2021/018965 (04.02.2021 Gazette 2021/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 29.07.2019 IT 201900013236 (71) Applicant: Epi-C S.r.L. 80138 Napoli (NA) (IT)	(72) Inventors: ALTUCCI, Lucia 80138 Napoli (NA) (IT) NEBBIOSO, Angela 80138 Napoli (NA) (IT) SCISCIOLA, Lucia 80138 Napoli (NA) (IT) (74) Representative: Pace Napoleone, Maria et al De Simone & Partners S.r.l. Via Vincenzo Bellini, 20 00198 Roma 00198 Roma (IT)