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EP 4 010 039 A1

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(43) Date of publication: 15.06.2022 Bulletin 2022/24 (21) Application number: 20851133.7 (22) Date of filing: 05.08.2020

(51) International Patent Classification (IPC):  A61L 27/04(2006.01) A61B 17/58(2006.01) A61F 2/28(2006.01) (52) Cooperative Patent Classification (CPC): A61B 17/58; A61F 2/28; A61L 2430/02; A61L 2420/00; A61L 2300/102; A61L 31/088; A61L 27/306; A61L 2400/18; A61L 27/303; A61L 31/084; A61B 17/866; A61F 2/30767; A61F 2002/30003; A61F 2002/3006; A61F 2002/3093; A61F 2002/2817; A61F 2310/0088 (86) International application number: PCT/TR2020/050692 (87) International publication number: WO 2021/025655 (11.02.2021 Gazette 2021/06)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 06.08.2019 TR 201911986 (71) Applicants: Istanbul Teknik Universitesi 34469 Istanbul (TR) Yeditepe Universitesi 34755 Istanbul (TR) Istanbul Universitesi Rektorlugu Faith/Istanbul (TR) Yildiz Teknik Universitesi 34220 Istanbul (TR)

(72) Inventors: URGEN, Mustafa Kamil Be ikta /Istanbul (TR) KAZMANLI, Muhammet Kursat Istanbul (TR) KOK, Fatma Nese 34469 Maslak/Istanbul (TR) OZTURK, Yetkin 34469 Istanbul (TR) KACAR, Erkan Sar yer/ Istanbul (TR) TORUN KOSE, Gamze 34755 Ata ehir/Istanbul (TR) SABOUNI, Kenda Ata ehir/Istanbul (TR) SOLAKOGLU, Seyhun Fatih/Istanbul (TR) MUTLU, Hasan Serdar Fatih/Istanbul (TR) ONDER, Sakip Esenler/Istanbul (TR) (74) Representative: Berkkam, Ayfer  Berkkam Patent Consulting Büklüm Sokak, No. 5/16-3 06680 Kavaklidere Ankara 06680 Kavaklidere Ankara (TR)