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EP 4 021 533 A1

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(43) Date of publication: 06.07.2022 Bulletin 2022/27 (21) Application number: 19787489.4 (22) Date of filing: 26.08.2019

(51) International Patent Classification (IPC):  A61M 5/155(2006.01) A61M 5/00(2006.01) A61M 5/168(2006.01) A61M 5/142(2006.01) (52) Cooperative Patent Classification (CPC): A61M 5/155; A61M 5/16827; A61M 5/007; A61M 2205/12; A61M 2205/128; A61M 2205/123; A61M 2205/50; A61M 2005/14208 (86) International application number: PCT/NL2019/050547 (87) International publication number: WO 2021/040513 (04.03.2021 Gazette 2021/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: Solstice Pharmaceuticals B.V. 7521 PL Enschede (NL)

(72) Inventors: VAN HOEVE, Willem 7522 HC Enschede (NL) GIANNASI, Katharine Jennifer 7522 HC Enschede (NL) BRAMER, Koen Joannes Jonathan 7671 PH Vriezenveen (NL) DE VARGAS SERRANO, Miguel 7512 HK Enschede (NL) LUCASSEN, Koen Rik 7597 NE Saasveld (NL) VAN DER PLAS, Renzo Bouwe 7312AN Apeldoorn (NL) PENTERMAN, Roel 7555 VX Hengelo (NL) EILANDER, Jan Wiebe 7558 MA Hengelo (NL) HEIJDENS, Erik Jan Herman 7577 BT Oldenzaal (NL) VAN VOORTHUIZEN, Vivian Anoek 7521 ZD Enschede (NL) (74) Representative: Arnold & Siedsma  Bezuidenhoutseweg 57 2594 AC The Hague 2594 AC The Hague (NL)