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EP 4 021 912 A1

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(43) Date of publication: 06.07.2022 Bulletin 2022/27 (21) Application number: 20857153.9 (22) Date of filing: 28.08.2020

(51) International Patent Classification (IPC):  C07F 9/6558(2006.01) A61K 31/675(2006.01) C07D 401/06(2006.01) A61K 31/4439(2006.01) A61P 35/00(2006.01) C07D 401/14(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07D 401/06; C07D 401/14; C07F 9/65583; C07D 405/12 (86) International application number: PCT/CA2020/051177 (87) International publication number: WO 2021/035360 (04.03.2021 Gazette 2021/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 30.08.2019 CN 201910817505 30.08.2019 CN 201910818675 30.08.2019 CN 201910818779 25.03.2020 US 202062994364 P (71) Applicant: Risen (Suzhou) Pharma Tech Co., Ltd. Suzhou, Jiangsu 215000 (CN)

(72) Inventors: LU, Jiasheng Shanghai 201702 (CN) GU, Jiamin Suzhou, Jiangsu 215000 (CN) CHEN, Gang Suzhou, Jiangsu 215000 (CN) ZHANG, Qiguo Suzhou, Jiangsu 215000 (CN) SUN, Chengyong Suzhou, Jiangsu 215000 (CN) KONG, Xianqi Québec H9B 3J7 (CA) (74) Representative: Høiberg P/S  Adelgade 12 1304 Copenhagen K 1304 Copenhagen K (DK)