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EP 4 025 689 A1

(12)

(43) Date of publication: 13.07.2022 Bulletin 2022/28 (21) Application number: 20775408.6 (22) Date of filing: 04.09.2020

(51) International Patent Classification (IPC):  C12N 5/0783(2010.01) C12N 9/02(2006.01) C07K 14/705(2006.01) (52) Cooperative Patent Classification (CPC): C12N 5/0636; C07K 14/70578; C07K 14/70575; C07K 14/7051; C12N 9/0071; C07K 2319/03; C12N 2510/00; C12N 2501/515; A61K 35/17; C07K 14/70539; C12N 9/22 (86) International application number: PCT/IB2020/058280 (87) International publication number: WO 2021/044378 (11.03.2021 Gazette 2021/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 06.09.2019 US 201962897016 P 30.10.2019 US 201962927764 P 04.06.2020 US 202063034646 P (71) Applicant: CRISPR Therapeutics AG 6300 Zug (CH)	(72) Inventors: TERRETT, Jonathan Alexander Cambridge, Massachusetts 02139 (US) KALAITZIDIS, Demetrios Cambridge, Massachusetts 02139 (US) WALDNER, Hanspeter Cambridge, Massachusetts 02139 (US) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstraße 3 81675 München 81675 München (DE)