(19)
(11) EP 4 025 911 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
28.08.2024 Bulletin 2024/35

(45) Mention of the grant of the patent:
26.06.2024 Bulletin 2024/26

(21) Application number: 20797166.4

(22) Date of filing: 04.09.2020
(51) International Patent Classification (IPC): 
G01N 33/543(2006.01)
 G01N 21/00(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 33/5432; G01N 21/554; G01N 21/76; G01N 21/64
(86) International application number:
PCT/IB2020/058284
(87) International publication number:
WO 2021/044381 (11.03.2021 Gazette 2021/10)

(54)

CONJUGATES COMPOSED OF MEMBRANE-TARGETING PEPTIDES FOR EXTRACELLULAR VESICLES ISOLATION, ANALYSIS AND THEIR INTEGRATION THEREOF

KONJUGATE AUS AUF MEMBRANEN ABZIELENDEN PEPTIDEN ZUR ISOLIERUNG EXTRAZELLULÄRER VESIKEL, ANALYSE UND INTEGRATION DAVON

CONJUGUÉS COMPOSÉS DE PEPTIDES CIBLANT UNE MEMBRANE POUR L'ISOLEMENT, L'ANALYSE DE VÉSICULES EXTRACELLULAIRES ET LEUR INTÉGRATION

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 06.09.2019 US 201962897042 P

(43) Date of publication of application:
13.07.2022 Bulletin 2022/28

(73) Proprietors:
  • Gori, Alessandro
    20862 Arcore (IT)
  • Cretich, Marina
    20147 Milano (IT)

(72) Inventors:
  • Alessandro GORI
    20862 Arcore (IT)
  • Marina CRETICH
    20147 Milano (IT)
  • Marcella CHIARI
    20131 Milano (IT)

(74) Representative: Zaccaro, Elisabetta et al
Notarbartolo & Gervasi S.p.A. Viale Achille Papa, 30
20149 Milano
20149 Milano (IT)


(56) References cited: : 
EP-A1- 2 491 952
   
  • KULAGINA NADEZHDA V ET AL: "Antimicrobial peptides for detection of bacteria in biosensor assays", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, vol. 77, no. 19, 1 October 2005 (2005-10-01), pages 6504 - 6508, XP002472240, ISSN: 0003-2700, DOI: 10.1021/AC050639R
  • JONEL P. SALUDES ET AL: "Detection of Highly Curved Membrane Surfaces Using a Cyclic Peptide Derived from Synaptotagmin-I", ACS CHEMICAL BIOLOGY, vol. 7, no. 10, 17 July 2012 (2012-07-17), pages 1629 - 1635, XP055767898, ISSN: 1554-8929, DOI: 10.1021/cb3002705
  • JONEL P. SALUDES ET AL: "Multivalency amplifies the selection and affinity of bradykinin-derived peptides for lipid nanovesicles", MOLECULAR BIOSYSTEMS, vol. 9, no. 8, 1 January 2013 (2013-01-01), GB, pages 2005, XP055767902, ISSN: 1742-206X, DOI: 10.1039/c3mb70109c
  • ALESSANDRO GORI ET AL: "Membrane-binding peptides for extracellular vesicles on-chip analysis", JOURNAL OF EXTRACELLULAR VESICLES, vol. 9, no. 1, 17 April 2020 (2020-04-17), pages 1751428, XP055767519, ISSN: 2001-3078, DOI: 10.1080/20013078.2020.1751428
  • ALESSANDRO GORI ET AL: "Membrane-Binding Peptides for Extracellular Vesicles On-Chip Analysis Manuscript", CHEMRXIV, 25 October 2019 (2019-10-25), XP055767838, Retrieved from the Internet <URL:https://s3-eu-west-1.amazonaws.com/itempdf74155353254prod/9885167/Membrane-Binding_Peptides_for_Extracellular_Vesicles_On-Chip_Analysis_v2.pdf> [retrieved on 20210122], DOI: 10.26434/chemrxiv.9885167.v2
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).