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(11)

EP 4 031 655 A2

(12)

(88) Date of publication A3: 29.04.2021 (43) Date of publication: 27.07.2022 Bulletin 2022/30 (21) Application number: 20865932.6 (22) Date of filing: 16.09.2020

(51) International Patent Classification (IPC):  C12N 5/078(2010.01) C07K 19/00(2006.01) C07K 16/30(2006.01) A61K 39/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 35/17; A61K 39/0011; A61K 39/39558; A61K 45/06; A61K 2039/505; A61K 2039/5158; A61P 37/06; C07K 16/2887; C12N 5/0636; C12N 2501/91; C12N 2529/00; C12N 2510/00; C07K 14/7051; C07K 2317/622; A61K 2039/5156; A61P 35/04   C-Sets: A61K 39/39558, A61K 2300/00; (86) International application number: PCT/IL2020/051011 (87) International publication number: WO 2021/053667 (25.03.2021 Gazette 2021/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 19.09.2019 US 201916576676 (71) Applicant: ENLIVEX THERAPEUTICS RDO LTD 7403618 Nes-Ziona (IL)	(72) Inventors: NOVIK, Shai 4721249 Ramat Hasharon (IL) MEVORACH, Dror 9574630 Jerusalem (IL) (74) Representative: Pearl Cohen Zedek Latzer Baratz UK LLP  The Gridiron Building One Pancras Square London N1C 4AG London N1C 4AG (GB)