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(11)

EP 4 031 657 A1

(12)

(43) Date of publication: 27.07.2022 Bulletin 2022/30 (21) Application number: 20786122.0 (22) Date of filing: 17.09.2020

(51) International Patent Classification (IPC):  C12N 9/02(2006.01) C12P 7/22(2006.01) C12P 17/06(2006.01) C12N 15/52(2006.01) C12P 7/42(2006.01) C12N 15/82(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/0004; C12Y 121/03007; C12P 17/06; C12P 7/42; C12N 15/52; C07K 14/415 (86) International application number: PCT/US2020/051261 (87) International publication number: WO 2021/055597 (25.03.2021 Gazette 2021/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 18.09.2019 US 201962902300 P (71) Applicant: Demetrix, Inc. Berkeley, CA 94710 (US)	(72) Inventors: HORWITZ, Andrew Berkeley, California 94710 (US) WONG, Jeff Berkeley, California 94710 (US) PLATT, Darren Berkeley, California 94710 (US) UBERSAX, Jeff Berkeley, California 94710 (US) (74) Representative: Cooley (UK) LLP  22 Bishopsgate London EC2N 4BQ London EC2N 4BQ (GB)