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EP 4 037 720 A1

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(43) Date of publication: 10.08.2022 Bulletin 2022/32 (21) Application number: 20871478.2 (22) Date of filing: 02.10.2020

(51) International Patent Classification (IPC):  A61L 15/62(2006.01) A61L 15/28(2006.01) A61F 13/53(2006.01) A61F 13/44(2006.01) A61L 15/60(2006.01) A61F 13/15(2006.01) A61F 13/42(2006.01) (52) Cooperative Patent Classification (CPC): A61L 15/62; A61L 15/60; A61L 15/28; A61F 13/15252   C-Sets: A61L 15/28, C08L 3/02; (86) International application number: PCT/US2020/054028 (87) International publication number: WO 2021/067769 (08.04.2021 Gazette 2021/14)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 04.10.2019 US 201916592948 01.11.2019 US 201962929438 P 30.09.2020 US 202017038954 30.09.2020 US 202017039101 (71) Applicant: Tethis, Inc. Raleigh, North Carolina 27616 (US)

(72) Inventors: CHAN, Ryan Nicholas Raleigh, North Carolina 27616 (US) COX, Gordon Sidney Durham, North Carolina 27707 (US) DAVIS, Hailey Katherine Raleigh, North Carolina 27607 (US) NETTEL, Vladimiro Kirkland, Québec H9J 3Y6 (CA) ROBINSON, James Clayton Weddington, North Carolina 28104 (US) WEITKAMP, Robin Raleigh, North Carolina 27601 (US) (74) Representative: Murgitroyd & Company  Murgitroyd House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)