(19)
(11) EP 4 038 385 A1

(12)

(43) Date of publication:
10.08.2022 Bulletin 2022/32

(21) Application number: 20792869.8

(22) Date of filing: 30.09.2020
(51) International Patent Classification (IPC): 
G01N 33/50(2006.01)
G01N 33/533(2006.01)
 A61B 5/00(2006.01)
G01N 33/543(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 33/533; G01N 33/54353; B82Y 30/00
(86) International application number:
PCT/US2020/053500
(87) International publication number:
WO 2021/067411 (08.04.2021 Gazette 2021/14)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 30.09.2019 US 201962908023 P
01.06.2020 WO PCT/US2020/035568
01.06.2020 WO PCT/US2020/035574

(71) Applicant: Michigan Technological University
Houghton, Michigan 49931 (US)

(72) Inventors:
  • YAP, Yoke Khin
    Houghton, Michigan 49931 (US)
  • ZHANG, Dongyan
    Houghton, Michigan 49931 (US)
  • YAPICI, Nazmiye
    South Lyon, Michigan 48178 (US)
  • LIU, Xiuling
    Ann Arbor, Michigan 48104 (US)

(74) Representative: Dehns 
St. Bride's House 10 Salisbury Square
London EC4Y 8JD
London EC4Y 8JD (GB)

   


(54) COMPOSITE HIGH-BRIGHTNESS FLUOROPHORES WITH CONTROLLABLE SPECTRA SHAPES AND METHOD OF USING COMPOSITE HIGH-BRIGHTNESS FLUOROPHORES