(19)

(11)

EP 4 041 227 A1

(12)

(43) Date of publication: 17.08.2022 Bulletin 2022/33 (21) Application number: 20886771.3 (22) Date of filing: 09.11.2020

(51) International Patent Classification (IPC):  A61K 31/4188(2006.01) A61K 47/14(2017.01) A61P 35/00(2006.01) A61K 31/17(2006.01) A61K 9/51(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; A61K 47/6929 (86) International application number: PCT/TR2020/051062 (87) International publication number: WO 2021/096464 (20.05.2021 Gazette 2021/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.11.2019 TR 201917444 14.05.2020 TR 202007578 (71) Applicant: Ege Universitesi 35100 Izmir (TR)	(72) Inventors: SANLIER, Senay 35040 Bornova/ Izmir (TR) AK, Güliz 35040 Bornova/ Izmir (TR) YILMAZ, Habibe 35040 Bornova/ Izmir (TR) ÜNAL, Ayse 35040 Bornova/ Izmir (TR) KARAKAYALI, Tugba 35040 Bornova/ Izmir (TR) SARI TURGUT, Özge 35040 Bornova/ Izmir (TR) (74) Representative: Yalçiner Patent and Consulting Ltd.  Tunus Caddesi 85/3-4 Kavaklidere Ankara Ankara (TR)