(19)
(11) EP 4 056 206 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
19.02.2025 Bulletin 2025/08

(45) Mention of the grant of the patent:
01.01.2025 Bulletin 2025/01

(21) Application number: 21162122.2

(22) Date of filing: 11.03.2021
(51) International Patent Classification (IPC): 
A61L 27/22(2006.01)
A61L 27/38(2006.01)
A61L 27/52(2006.01)
 A61L 27/24(2006.01)
A61L 27/36(2006.01)
(52) Cooperative Patent Classification (CPC):
A61L 27/3808; A61L 27/3839; A61L 27/222; A61L 27/24; A61L 2430/16; A61L 2430/40; A61L 27/52; A61L 27/3683

(54)

ARTIFICIAL ENDOTHELIAL KERATOPLASTY GRAFT AND METHODS OF PREPARATION THEREOF

KÜNSTLICHES ENDOTHELIALES KERATOPLASTIE-TRANSPLANTAT UND VERFAHREN ZU DESSEN HERSTELLUNG

GREFFE PAR KÉRATOPLASTIE ENDOTHÉLIALE ARTIFICIELLE ET SES MÉTHODES DE PRÉPARATION

(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(43) Date of publication of application:
14.09.2022 Bulletin 2022/37

(73) Proprietor: Precise Bio Inc.
Greensboro NC 27410 (US)

(72) Inventors:
  • BATT, Aryeh
    9044000 Har Hebron (IL)
  • EITAN, Amos
    93123 Jerusalem (IL)
  • EISENBACH, Ariel
    44865 Zufim (IL)
  • HAYARDENI, Yishay
    Greensboro, NC 27410 (US)
  • KHAN, Mehwish
    High Point, NC 27262 (US)
  • MARCUS, Michal
    4995000 Nechalim (IL)
  • NEPAL, Kanti
    Winston Salem, NC 27107 (US)
  • NGUYEN, Khanh
    Winston Salem, NC 27104 (US)
  • SHAV, Lior
    Glen Rock, NJ 07452 (US)
  • WU, Yan
    Winston Salem, NC 27101 (US)

(74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB 
Siebertstraße 3
81675 München
81675 München (DE)


(56) References cited: : 
EP-A1- 2 468 312
EP-A1- 2 755 598
EP-B1- 2 483 332
WO-A1-2007/043255
 EP-A1- 2 483 332
EP-A1- 2 940 126
EP-B1- 2 755 598
WO-A1-2019/198086
   
  • RIZWAN MUHAMMAD ET AL: "Sequentially-crosslinked bioactive hydrogels as nano-patterned substrates with customizable stiffness and degradation for corneal tissue engineering applications", BIOMATERIALS, ELSEVIER, AMSTERDAM, NL, vol. 120, 23 December 2016 (2016-12-23), pages 139 - 154, XP029879408, ISSN: 0142-9612, DOI: 10.1016/J.BIOMATERIALS.2016.12.026
  • AN JEONG-HEE ET AL: "Tissue engineered ultra-thin descemet stripping corneal endothelial layers using porcine cornea and stem cells", EXPERIMENTAL EYE RESEARCH, ACADEMIC PRESS LTD, LONDON, vol. 199, 14 August 2020 (2020-08-14), XP086286432, ISSN: 0014-4835, [retrieved on 20200814], DOI: 10.1016/J.EXER.2020.108192
 
Remarks:
The file contains technical information submitted after the application was filed and not included in this specification
 
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).