(19)

(11)

EP 4 058 470 A2

(12)

(88) Date of publication A3: 17.06.2021 (43) Date of publication: 21.09.2022 Bulletin 2022/38 (21) Application number: 20887138.4 (22) Date of filing: 16.11.2020

(51) International Patent Classification (IPC):  C07K 14/47(2006.01) A61K 47/64(2017.01) C07K 14/16(2006.01) A61K 38/17(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/705 (86) International application number: PCT/US2020/060681 (87) International publication number: WO 2021/097407 (20.05.2021 Gazette 2021/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 15.11.2019 US 201962936025 P (71) Applicant: The Regents of the University of Colorado, A Body Corporate Denver, CO 80203 (US)	(72) Inventor: HERSON, Paco, S. Denver, CO 80238 (US) (74) Representative: Predazzi, Valentina et al Società Italiana Brevetti S.p.A. Piazza di Pietra, 39 00186 Roma 00186 Roma (IT)