OLIGONUCLEOTIDE PRIMERS FOR THE CHARACTERIZATION OF THE CAG TRACT AND MEASUREMENT OF MUTANT MRNA IN THE CONTEXT OF POLYGLUTAMINE DISORDERS - Patent 4058602

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EP 4 058 602 A1

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(43)	Date of publication:
	21.09.2022 Bulletin 2022/38

(21)	Application number: 20824634.8

(22)	Date of filing: 13.11.2020

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International Patent Classification (IPC):

C12Q 1/6883^(2018.01)

(52)	Cooperative Patent Classification (CPC):
	C12Q 1/6883; C12Q 2600/156

(86)	International application number:
	PCT/IB2020/060705

(87)	International publication number:
	WO 2021/095001 (20.05.2021 Gazette 2021/20)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA ME
	Designated Validation States:
	KH MA MD TN

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Priority:

13.11.2019 PT 2019115909

(71)	Applicants:
	Universidade de Coimbra 3004-531 Coimbra (PT) Centro de Neurociências e Biologia Celular 3004-504 Coimbra (PT)

(72)	Inventors:
	GONÇALVES PEREIRA NOBRE, Rui Jorge 3000-323 Coimbra (PT) MONTEIRO LOPES, Sara Isabel 6300-661 Guarda (PT) MORGADO PEREIRA DE ALMEIDA, Luís Fernando 3000-032 Coimbra (PT)

(74)	Representative: Patentree
	Edificio Net Rua de Salazares, 842 4149-002 Porto 4149-002 Porto (PT)

(54)	OLIGONUCLEOTIDE PRIMERS FOR THE CHARACTERIZATION OF THE CAG TRACT AND MEASUREMENT OF MUTANT MRNA IN THE CONTEXT OF POLYGLUTAMINE DISORDERS