(19)

(11)

EP 4 061 808 A1

(12)

(43) Date of publication: 28.09.2022 Bulletin 2022/39 (21) Application number: 20888871.9 (22) Date of filing: 17.11.2020

(51) International Patent Classification (IPC):  C07D 401/04(2006.01) C07D 405/14(2006.01) C07D 401/14(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/18; A61K 31/4439; A61K 31/46; A61K 9/1652   C-Sets: A61K 31/4439, A61K 2300/00; A61K 31/46, A61K 2300/00; (86) International application number: PCT/US2020/060859 (87) International publication number: WO 2021/101875 (27.05.2021 Gazette 2021/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 18.11.2019 US 201962936837 P 27.05.2020 US 202063030780 P (71) Applicant: Karuna Therapeutics, Inc. Boston, MA 02110 (US)	(72) Inventors: BRANNAN, Stephen Boston, Massachusetts 02110 (US) MILLER, Andrew Boston, Massachusetts 02110 (US) (74) Representative: Bridle, Andrew Barry  Bridle Intellectual Property Limited 6F Thomas Way Lakesview Internat. Business Park Canterbury, Kent CT3 4JZ Canterbury, Kent CT3 4JZ (GB)