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EP 4 072 534 A1

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(43) Date of publication: 19.10.2022 Bulletin 2022/42 (21) Application number: 20825241.1 (22) Date of filing: 04.12.2020

(51) International Patent Classification (IPC):  A61K 9/68(2006.01) A61K 47/26(2006.01) A61K 47/44(2017.01) A61K 31/185(2006.01) A61K 31/198(2006.01) A61K 31/522(2006.01) A61K 36/53(2006.01) A61K 47/10(2017.01) A61K 47/36(2006.01) A61K 47/12(2006.01) A61K 31/197(2006.01) A61K 31/375(2006.01) A61K 36/258(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0058; A61K 47/26; A61K 47/36; A61K 47/44; A61K 47/12; A61K 31/198; A61K 31/197; A61K 31/522; A61K 31/185; A61K 31/375; A61K 36/53; A61K 36/258; A61K 31/405; A61K 31/4415; A61K 31/714; A61K 31/7068; A61K 31/685   C-Sets: A61K 31/405, A61K 2300/00; A61K 31/4415, A61K 2300/00; A61K 31/714, A61K 2300/00; A61K 31/375, A61K 2300/00; A61K 31/7068, A61K 2300/00; A61K 36/53, A61K 2300/00; A61K 31/198, A61K 2300/00; A61K 36/258, A61K 2300/00; A61K 31/197, A61K 2300/00; A61K 31/685, A61K 2300/00; A61K 31/522, A61K 2300/00; A61K 31/185, A61K 2300/00; (86) International application number: PCT/IB2020/061472 (87) International publication number: WO 2021/116854 (17.06.2021 Gazette 2021/24)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 09.12.2019 US 201916706974 08.06.2020 US 202063036254 P (71) Applicant: Nicoventures Trading Limited London Greater London WC2R 3LA (GB)

(72) Inventors: ODEN, Ross Jay London Greater London WC2R 3LA (GB) LAMPE, Matthew Evan London Greater London WC2R 3LA (GB) SPIELBAUER, Kristen Ann London Greater London WC2R 3LA (GB) ZAWADZKI, Michael Andrew London Greater London WC2R 3LA (GB) GERARDI, Anthony Richard Winston-Salem, North Carolina 27104 (US) (74) Representative: Newcombe, Christopher David et al Venner Shipley LLP 200 Aldersgate London EC1A 4HD London EC1A 4HD (GB)