(19)
(11) EP 4 076 659 A1

(12)

(43) Date of publication:
26.10.2022 Bulletin 2022/43

(21) Application number: 19835811.1

(22) Date of filing: 19.12.2019
(51) International Patent Classification (IPC): 
A61P 33/06(2006.01)
C07D 498/08(2006.01)
 A61K 31/33(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 498/08; A61P 33/06; Y02A 50/30
(86) International application number:
PCT/IB2019/061066
(87) International publication number:
WO 2021/123883 (24.06.2021 Gazette 2021/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(71) Applicant: Latvian Institute Of Organic Synthesis
1006 Riga (LV)

(72) Inventors:
  • JIRGENSONS, Aigars
    1013 Riga (LV)
  • KOVADA, Vadims
    1035 Riga (LV)
  • BOBROVS, Raitis
    2113 Kekava (LV)
  • SUNA, Edgars
    1004 Riga (LV)
  • JAUDZEMS, Kristaps
    1079 Riga (LV)
  • RASINA, Dace
    2169 Salaspils (LV)
  • ZOGOTA, Rimants
    1024 Riga (LV)

(74) Representative: Madgwick, Paul Roland 
Ruschke Madgwick Seide & Kollegen Patentanwälte Patent Attorney (UK) PartG mbB Postfach 86 06 29
81633 München
81633 München (DE)

   


(54) MACROCYCLIC AMIDES ACTING AS PLASMEPSIN INHBITORS FOR THE TREATMENT OF MALARIA