(19)
(11) EP 4 085 933 A3

(12) EUROPEAN PATENT APPLICATION

(88) Date of publication A3:
11.01.2023 Bulletin 2023/02

(43) Date of publication A2:
09.11.2022 Bulletin 2022/45

(21) Application number: 22162958.7

(22) Date of filing: 12.04.2017
(51) International Patent Classification (IPC): 
A61K 48/00(2006.01)
C07K 14/035(2006.01)
C12N 9/02(2006.01)
C12N 15/76(2006.01)
C07D 307/33(2006.01)
C07K 14/36(2006.01)
C12N 15/52(2006.01)
C12P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 14/36; C12N 15/52; C12N 15/76; C12P 35/00; C12N 9/0071; C12Y 114/00
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
MA MD

(30) Priority: 12.04.2016 US 201662321439 P

(62) Application number of the earlier application in accordance with Art. 76 EPC:
17783058.5 / 3442599

(71) Applicant: Ginkgo Bioworks, Inc.
Boston, MA 02210 (US)

(72) Inventors:
  • Bowman, Brian R.
    New Rochelle, NY 10804 (US)
  • Blodgett, Joshua A.V.
    Webster Groves, MO 63119 (US)
  • Verdine, Gregory L.
    Boston, MA 02110 (US)
  • Gray, Daniel C.
    Medford, MA 02155 (US)
  • Morgenstern, Jay P.
    Boston, MA 02115 (US)
  • Foulston, Lucy
    Medford, MA 02115 (US)
  • Robison, Keith
    Andover, MA 01810 (US)

(74) Representative: Hoffmann Eitle 
Patent- und Rechtsanwälte PartmbB Arabellastraße 30
81925 München
81925 München (DE)

   


(54) COMPOSITIONS AND METHODS FOR THE PRODUCTION OF COMPOUNDS


(57) The present disclosure provides nucleic acids encoding a Large ATP-binding regulator of the LuxR family (LAL) of transcription factors, vectors and host cells including such nucleic acids, and methods for producing compounds (e.g., polyketides or β-lactam compounds) with such nucleic acids, vectors, and/or host cells.







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