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(11)

EP 4 087 940 A1

(12)

(43) Date of publication: 16.11.2022 Bulletin 2022/46 (21) Application number: 21738150.8 (22) Date of filing: 11.01.2021

(51) International Patent Classification (IPC):  C12Q 1/68(2018.01) C12Q 1/6886(2018.01) G16B 20/20(2019.01) C12Q 1/6869(2018.01) G16B 20/00(2019.01) G16B 30/00(2019.01) (52) Cooperative Patent Classification (CPC): G16B 20/20 (86) International application number: PCT/US2021/012945 (87) International publication number: WO 2021/142437 (15.07.2021 Gazette 2021/28)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 10.01.2020 US 202062959805 P 13.07.2020 US 202063051227 P (71) Applicant: Gritstone bio, Inc. Emeryville CA 94608 (US)	(72) Inventors: SUN, James, Xin Emeryville, CA 94608 (US) DAVIS, Matthew, Joseph Emeryville, CA 94608 (US) SCHENK, Desiree Emeryville, CA 94608 (US) NAVARRO GOMEZ, Daniel Emeryville, CA 94608 (US) (74) Representative: Elkington and Fife LLP  Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)