(19)

(11)

EP 4 090 686 A2

(12)

(88) Date of publication A3: 11.11.2021 (43) Date of publication: 23.11.2022 Bulletin 2022/47 (21) Application number: 21741991.0 (22) Date of filing: 15.01.2021

(51) International Patent Classification (IPC):  C07K 16/30(2006.01) A61P 17/06(2006.01) G01N 33/58(2006.01) A61P 35/00(2006.01) A61P 37/02(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/30; C07K 16/00; C07K 2317/60; C07K 16/46; C07K 2319/00; C07K 2317/31; C07K 16/28; C07K 16/2809; C07K 16/2818; C07K 2317/70 (86) International application number: PCT/US2021/013688 (87) International publication number: WO 2021/146590 (22.07.2021 Gazette 2021/29)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 17.01.2020 US 202062962555 P (71) Applicant: Aetio Biotherapy, Inc. Dallas, TX 75247 (US)	(72) Inventor: TSENG, Kuo-Fu Dallas, TX 75238 (US) (74) Representative: Barker Brettell LLP  100 Hagley Road Edgbaston Birmingham B16 8QQ Birmingham B16 8QQ (GB)