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(11)

EP 4 096 552 A1

(12)

(43) Date of publication: 07.12.2022 Bulletin 2022/49 (21) Application number: 21707370.9 (22) Date of filing: 01.02.2021

(51) International Patent Classification (IPC):  A61B 34/30(2016.01) A61B 90/00(2016.01) A61B 34/32(2016.01) (52) Cooperative Patent Classification (CPC): A61B 34/30; A61B 2034/2055; A61B 34/32; A61B 90/37; A61B 2090/376; A61B 2090/061; A61B 2090/064 (86) International application number: PCT/IB2021/050767 (87) International publication number: WO 2021/152556 (05.08.2021 Gazette 2021/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 31.01.2020 IT 202000001900 (71) Applicants: Università Campus Bio-Medico di Roma 00128 Roma (IT) MASMEC S.p.A. 70026 Modugno (IT)	(72) Inventors: ZOLLO, Loredana 00128 Roma RM (IT) LAURETTI, Clemente 00128 Roma RM (IT) CORDELLA, Francesca 00128 Roma RM (IT) (74) Representative: Papa, Elisabetta et al Società Italiana Brevetti S.p.A Piazza di Pietra, 39 00186 Roma 00186 Roma (IT)