(19)

(11)

EP 4 103 157 A1

(12)

(43) Date of publication: 21.12.2022 Bulletin 2022/51 (21) Application number: 21705444.4 (22) Date of filing: 09.02.2021

(51) International Patent Classification (IPC):  A61K 9/20(2006.01) A61K 31/155(2006.01) A61K 31/133(2006.01) A61K 31/522(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/2059; A61K 9/2027; A61K 9/2013; A61K 9/2009; A61K 31/133; A61K 31/155; A61K 31/522   C-Sets: A61K 31/155, A61K 2300/00; A61K 31/133, A61K 2300/00; A61K 31/522, A61K 2300/00; (86) International application number: PCT/EP2021/053072 (87) International publication number: WO 2021/160608 (19.08.2021 Gazette 2021/33)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 13.02.2020 EP 20460012 (71) Applicant: Zaklady Farmaceutyczne Polpharma S.A. 83-200 Starogard Gdanski (PL)	(72) Inventors: KRUSI SKI, Tomasz 54-130 Wroc aw (PL) PRZERADA, Szymon 83-200 Starogard Gda ski (PL) HRAKOVSKY, Julia 81-379 Gdynia (PL) SKOCZE , Przemys aw 83-010 Straszyn (PL) (74) Representative: Elkington and Fife LLP  Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)