(19)

(11)

EP 4 103 284 A1

(12)

(43) Date of publication: 21.12.2022 Bulletin 2022/51 (21) Application number: 21708300.5 (22) Date of filing: 12.02.2021

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C12N 5/0783(2010.01) C07K 14/725(2006.01) C12N 15/85(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/7051; C12N 5/0636; C12N 2510/00; A61P 35/00; C07K 2319/00; C07K 14/76; A61K 38/00; A61K 35/17; A61P 1/16; A61K 45/06 (86) International application number: PCT/GB2021/050341 (87) International publication number: WO 2021/161032 (19.08.2021 Gazette 2021/33)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 14.02.2020 US 202062976493 P (71) Applicant: Adaptimmune Limited Abingdon, Oxfordshire OX14 4RX (GB)	(72) Inventor: PUMPHREY, Nicholas Jonathan Abingdon Oxfordshire OX14 4RX (GB) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)