(19)

(11)

EP 4 107 160 A1

(12)

(43) Date of publication: 28.12.2022 Bulletin 2022/52 (21) Application number: 21710844.8 (22) Date of filing: 18.02.2021

(51) International Patent Classification (IPC):  C07D 498/22(2006.01) A61K 31/395(2006.01) C07D 513/22(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07D 498/22; C07D 513/22; A61P 35/00 (86) International application number: PCT/US2021/018520 (87) International publication number: WO 2021/168074 (26.08.2021 Gazette 2021/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 18.02.2020 US 202062978202 P (71) Applicant: Theseus Pharmaceuticals, Inc. Cambridge, MA 02139 (US)	(72) Inventors: HUANG, Wei-Sheng Cambridge, MA 02139 (US) SHAKESPEARE, William C. Cambridge, MA 02139 (US) EYERMANN, Charles J. Cambridge, MA 02139 (US) DALGARNO, David C. Cambridge, MA 02139 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)