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(11)

EP 4 110 400 A1

(12)

(43) Date of publication: 04.01.2023 Bulletin 2023/01 (21) Application number: 21709779.9 (22) Date of filing: 26.02.2021

(51) International Patent Classification (IPC):  A61K 47/54(2017.01) A61P 31/00(2006.01) A61K 47/64(2017.01) C07K 7/64(2006.01) (52) Cooperative Patent Classification (CPC): A61K 47/64; A61P 31/00; C07K 7/08; C07K 14/245; C07K 14/21; C07K 14/212 (86) International application number: PCT/GB2021/050490 (87) International publication number: WO 2021/171028 (02.09.2021 Gazette 2021/35)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 26.02.2020 GB 202002705 (71) Applicant: BicycleTX Limited Cambridge CB21 6GP (GB)

(72) Inventors: BALMFORTH, Matthew Cambridge CB33 3AT (GB) BESWICK, Paul Cambridge CB33 3AT (GB) DAWSON, Mike Cambridge CB22 3AT (GB) DODS, Rachel Cambridge CB22 3AT (GB) ROWLAND, Catherine Cambridge CB22 3AT (GB) SKYNNER, Michael Cambridge CB22 3AT (GB) RIETSCHOTEN, Katerine Van Cambridge CB22 3AT (GB) WAGSTAFF, James Cambridge CB22 3AT (GB) (74) Representative: Gibson, Mark  Sagittarius IP Marlow International Parkway Marlow SL7 1YL Marlow SL7 1YL (GB)