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(11)

EP 4 114 177 A1

(12)

(43) Date of publication: 11.01.2023 Bulletin 2023/02 (21) Application number: 21763705.7 (22) Date of filing: 05.03.2021

(51) International Patent Classification (IPC):  A01N 25/02(2006.01) A61L 2/18(2006.01) A01N 31/02(2006.01) (52) Cooperative Patent Classification (CPC): A01N 31/02; A61L 2/18; A01N 37/16; A01N 59/00; A01N 37/02; A01N 35/02; A01N 31/16; A01N 31/08; A01N 31/04; A61L 2/186   C-Sets: A01N 31/16, A01N 31/04, A01N 31/08, A01N 31/08, A01N 37/02, A01N 65/28; A01N 31/08, A01N 31/04, A01N 31/08, A01N 37/02, A01N 65/28; A01N 31/04, A01N 37/02, A01N 65/28; A01N 37/02, A01N 65/28; A01N 37/16, A01N 31/02, A01N 31/02, A01N 31/02, A01N 31/04, A01N 31/08, A01N 31/08, A01N 31/16, A01N 35/02, A01N 37/02, A01N 59/00, A01N 65/28; A01N 31/02, A01N 31/02, A01N 31/02, A01N 31/04, A01N 31/08, A01N 31/08, A01N 31/16, A01N 35/02, A01N 37/02, A01N 65/28; A01N 59/00, A01N 31/02, A01N 31/02, A01N 31/02, A01N 31/04, A01N 31/08, A01N 31/08, A01N 31/16, A01N 35/02, A01N 37/02, A01N 65/28; A01N 35/02, A01N 31/04, A01N 31/08, A01N 31/08, A01N 31/16, A01N 37/02, A01N 65/28; (86) International application number: PCT/US2021/021045 (87) International publication number: WO 2021/178774 (10.09.2021 Gazette 2021/36)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 05.03.2020 US 202062985783 P (71) Applicant: Markesbery Blue Pearl LLC Hebron, KY 41048 (US)	(72) Inventors: PANCHERI, Eugene J. Cincinnati, OH 45217 (US) MARKESBERY, W. Russell Hebron, KY 41048 (US) LAJINESS, Daniel H. Fairfield, OH 45014 (US) (74) Representative: Kuhnen & Wacker Patent- und Rechtsanwaltsbüro PartG mbB  Prinz-Ludwig-Straße 40A 85354 Freising 85354 Freising (DE)