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(11)

EP 4 118 210 A1

(12)

(43) Date of publication: 18.01.2023 Bulletin 2023/03 (21) Application number: 21768699.7 (22) Date of filing: 10.03.2021

(51) International Patent Classification (IPC):  C12N 15/62(2006.01) C12N 15/81(2006.01) A61K 39/215(2006.01) C07K 14/005(2006.01) C12N 7/00(2006.01) A61P 31/14(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/215; A61P 31/14; C07K 14/005; C12N 15/81; C12N 15/86; C12N 2710/10343; C12N 2770/20022; A61K 2039/542; A61K 2039/6031; A61K 2039/5256; C12N 2770/20034; C12N 2770/20071; C07K 2319/06 (86) International application number: PCT/US2021/021737 (87) International publication number: WO 2021/183665 (16.09.2021 Gazette 2021/37)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.03.2020 US 202062988328 P 14.04.2020 US 202063009960 P 14.04.2020 US 202063010010 P 26.05.2020 US 202016883263 01.08.2020 US 202063059975 P 11.08.2020 US 202063064157 P 24.11.2020 US 202063117460 P 24.11.2020 US 202063117922 P 24.11.2020 US 202063117847 P 26.11.2020 US 202063118697 P 08.01.2021 US 202163135380 P (71) Applicant: ImmunityBio, Inc. Culver City, CA 90232 (US)

(72) Inventors: SOON-SHIONG, Patrick Culver City, California 90232 (US) SIELING, Peter Culver City, California 90232 (US) SHIN, Annie Culver City, California 90232 (US) SENDER, Leonard Culver City, California 90232 (US) SAFRIT, Jeffrey Culver City, California 90232 (US) RICE, Adrian Culver City, California 90232 (US) RABIZADEH, Shahrooz Culver City, California 90232 (US) NIAZI, Kayvan Culver City, California 90232 (US) GEISSERT, Lise Culver City, California 90232 (US) GABITZSCH, Elizabeth Culver City, California 90232 (US) (74) Representative: AWA Sweden AB  Box 45086 104 30 Stockholm 104 30 Stockholm (SE)