(19)

(11)

EP 4 127 166 A2

(12)

(88) Date of publication A3: 11.11.2021 (43) Date of publication: 08.02.2023 Bulletin 2023/06 (21) Application number: 21780870.8 (22) Date of filing: 29.03.2021

(51) International Patent Classification (IPC):  C12N 15/10(1990.01) C12Q 1/686(2018.01) C12Q 1/6806(2018.01) C12Q 1/6876(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/70 (86) International application number: PCT/US2021/024596 (87) International publication number: WO 2021/202344 (07.10.2021 Gazette 2021/40)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 31.03.2020 US 202063002969 P (71) Applicant: BioSkryb Genomics, Inc. Durham, NC 27713 (US)	(72) Inventors: GAWAD, Charles Durham, North Carolina 27701 (US) WEST, Jay A.A. Durham, North Carolina 27701 (US) ZAWISTOWSKI, Jon Stanley Durham, North Carolina 27701 (US) (74) Representative: Wichmann, Hendrik  Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2 81541 München 81541 München (DE)