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EP 4 132 387 A1

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(43) Date of publication: 15.02.2023 Bulletin 2023/07 (21) Application number: 21718980.2 (22) Date of filing: 09.04.2021

(51) International Patent Classification (IPC):  A61B 17/28(1968.09) A61B 5/05(1968.09) A61B 90/30(2016.01) A61B 17/00(1968.09) A61B 5/00(1968.09) A61B 17/29(2006.01) A61B 90/00(2016.01) (52) Cooperative Patent Classification (CPC): A61B 17/29; A61B 2017/00022; A61B 2017/00057; A61B 2017/00106; A61B 2017/2927; A61B 90/30; A61B 2017/2829; A61B 2017/2825; A61B 2017/2926; A61B 2090/3784; A61B 2090/374; A61B 2090/373; A61B 2090/309; A61B 2017/00061; A61B 2034/2055; A61B 2090/365; A61B 90/361; A61B 2090/3941 (86) International application number: PCT/NL2021/050233 (87) International publication number: WO 2021/206557 (14.10.2021 Gazette 2021/41)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 09.04.2020 NL 2025324 (71) Applicant: Academisch Ziekenhuis Leiden (h.o.d.n. LUMC) 2333 ZA Leiden (NL)	(72) Inventors: VAN LEEUWEN, Sven 2333 ZA Leiden (NL) VAN OOSTEROM, Matthias 2333 ZA Leiden (NL) VAN LEEUWEN, Fijs 2333 ZA Leiden (NL) BOONEKAMP, Michael 2333 ZA Leiden (NL) VAN DER POEL, Henk 2333 ZA Leiden (NL) HOUWING, Krijn 2333 ZA Leiden (NL) (74) Representative: HGF  HGF BV Benoordenhoutseweg 46 2596 BC The Hague 2596 BC The Hague (NL)