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(11)

EP 4 132 471 A1

(12)

(43) Date of publication: 15.02.2023 Bulletin 2023/07 (21) Application number: 21713445.1 (22) Date of filing: 26.03.2021

(51) International Patent Classification (IPC):  A61K 9/14(1974.07) A61K 9/107(1990.01) A61K 47/10(1990.01) A61K 9/00(1968.09) A61K 31/045(1974.07) A61P 17/04(2000.01) (52) Cooperative Patent Classification (CPC): A61K 9/0014; A61K 9/107; A61K 9/143; A61K 31/045; A61K 47/10; A61P 17/04; A61K 9/145 (86) International application number: PCT/EP2021/058011 (87) International publication number: WO 2021/204568 (14.10.2021 Gazette 2021/41)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 07.04.2020 EP 20168596 (71) Applicants: Universität Basel 4001 Basel (CH) Universität Zürich 8006 Zürich (CH)	(72) Inventors: NAVARINI, Alexander 4153 Reinach (CH) OPPLIGER, Anna 8049 Zürich (CH) FRÖHLICH, Johannes 8702 Zollikon (CH) HEEB, Lukas 8600 Dübendorf (CH) (74) Representative: Schulz Junghans Patentanwälte PartGmbB  Großbeerenstraße 71 10963 Berlin 10963 Berlin (DE)