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EP 4 132 674 A1

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(43) Date of publication: 15.02.2023 Bulletin 2023/07 (21) Application number: 21792373.9 (22) Date of filing: 21.04.2021

(51) International Patent Classification (IPC):  B01D 17/00(1968.09) B01D 57/02(1980.01) B01D 17/06(1968.09) B01J 19/08(1980.01) (52) Cooperative Patent Classification (CPC): B01D 17/06; C12Q 1/6806; B01L 2200/16; B01L 2400/0481; B01L 2200/10; G01N 33/6818   C-Sets: C12Q 1/6806, C12Q 2535/122, C12Q 2537/159, C12Q 2565/629; (86) International application number: PCT/US2021/028471 (87) International publication number: WO 2021/216763 (28.10.2021 Gazette 2021/43)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 22.04.2020 US 202063014087 P 22.04.2020 US 202063014071 P 22.04.2020 US 202063014093 P 22.04.2020 US 202063014106 P 19.06.2020 US 202063041206 P 20.01.2021 US 202163139348 P 20.01.2021 US 202163139339 P 20.01.2021 US 202163139346 P 20.01.2021 US 202163139343 P (71) Applicant: Quantum-Si Incorporated Guilford, CT 06437 (US)

(72) Inventors: ROTHBERG, Jonathan, M. Miami Beach, FL 33139 (US) LEAMON, John, H. Stonington, CT 06378 (US) SCHULTZ, Jonathan, C. Guilford, CT 06437 (US) MILLHAM, Michele Guilford, CT 06437 (US) LV, Caixia Guilford, CT 06437 (US) HUANG, Haidong Madison, CT 06443 (US) NANI, Roger Madison, CT 06443 (US) AD, Omer Madison, CT 06443 (US) REED, Brian Madison, CT 06443 (US) DYER, Matthew Spring, TX 77386 (US) BOER, Robert, E. Westbrook, CT 06498 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)